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A ball and stick model of Human Insulin. Isolated on black.

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orange: RNA primer; red: RNA template; light blue: proofreading riboexonuclease; mid blue: helicase; dark blue: RNA directed RNA polymerase; violet: non structural proteins (NSPs).

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Mobile Network Data Technology, Global Communication, Speed

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p53 (blue) tagged with ubiquitin (yellow) is degraded into small peptides by a proteasome (violett). p53 prevents cancer formation and acts as a guardian of the genome. Mutations in the p53 gene contribute to about half of the cases of human cancer.

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Proteasomes are molecular machines for breaking down proteins called proteolysis, only target proteins that have been marked for destruction called ubiquitin to the target protein, 3d rendering

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Inside protein molecule

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Gamma secretase protein complex. Multi-subunit intramembrane protease that plays role in processing of proteins. 3D illustration.

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DNA mutation, a mutation is a change in a DNA sequence, mutations can result from DNA copying mistakes made during cell division.

DOT1L methylates a ubiquitinated nucleosome with the DNA methyl transferase I (mid) transfers a methyl group from S-adenosyl methionine (red) mostly to cytosine bases of the human DNA. Two ubiquitin molecules (light blue, right) binding to a nucleosome. Source: PDB entry 6NOG, 3PT6, 7XD0DOT!

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