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| Keywords: Writing by a Parkinson's disease patient.jpg Writing by a Parkinson's disease patient png en Example of writing by a patient with Parkinson's disease; possibly showing micrographia in addition to other abnormal characteristics Lectures on the diseases of the nervous system Published 1879 Second edition by H C Lea in Philadelphia Lecture V On paralysis agitans Page112 Specific image obtained from http //www archive org/stream/lecturesondiseas00charrich page/112/mode/2up Jean-Martin Charcot 1825 “ 1893 1879 PD-old-100 Text accompanying the image in the original source The tremor causes the handwriting to exhibit characters which are somewhat special When the disease is commencing the writing at first glance seems normal but when examined with a magnifying glass inequalities are perceived some parts being thicker and heavier than others Later on in the period of stationary intensity for instance the changes are more marked and consequently plainer The specimen Fig 7 p 112 represents the writing of a patient whose case we studied at the Hopital St Louis in 1869 The strokes forming the letters are very irregular and sinuous whilst the irregularities and sinuosities are of a very limited width Bourneville On a careful examination of this specimen of writing it will be perceived that the down-strokes are all with the exception of the first letter made with comparative firmness and are in fact nearly normal ” the finer up-strokes on the contrary are all tremulous in appearance and it is to the unsteadiness of these lines that the peculiar character of the writing here is principally due From this I would infer that the flexors of the fingers were at this stage of the disease less affected by tremor than the extensors and that amongst the latter the interossei were probably the earliest affected This inference will not be without interest for those who remember the attention which Dr Duchenne de Boulogne gave to the conduct of these muscles in the various paralytic and atrophic affections of the hand Sigerson PD-old-100 Parkinson's disease Jean-Martin Charcot | ||||
